Wednesday, March 18, 2015

Endorphins definition What are endorphins



Endorphin is a chemical substance made of proteins and produced in the pituitary gland of the brain. It acts on the central and the peripheral nervous systems in suppressing pain.
Enkephalin is a type of endorphin and also a natural pain killer, working to inhibit the transmission of pain in the pathway for pain perception. This lessens the emotional and the physical impact of pain.
Research is revealing how these two natural opiates might also serve other roles.
Enkephalin might be involved in the development of psycho-pathological behavior in some people. Endorphin might also exert profound effects on moods, higher production being associated with a persons sense of well-being.
Increased levels of these chemical substances might also prevent an immune system from being weakened by such psychological states as depression or bereavement.
People prone to depression, alcoholism, or drug addiction are often deficient in endorphin levels.

How to increase endorphin levels?

Regular aerobic exercise is believed to elevate endorphin levels.This is the so-called “runner’s high”.
Meditation, prayer and relaxation response training also elevate endorphin levels.
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Living Fertiliser Factory


The moisture-loving insectivorous plants that I grow in my conservatory stand in dishes of water, which inevitably accumulate a layer of ‘green slime’ on the surface. But this is no ordinary green slime. Under the microscope it’s revealed as a cyanobacterium (blue-green alga) called Nostoc, identifiable by those chains of small cells with occasional much larger ones interpolated along the rows. Those large cells are called heterocysts and the contain the enzymes that convert gaseous nitrogen in the atmosphere into soluble nitrogen compounds that plants need for their growth. These cells are living fertiliser factories. They’ve been providing an essential nutrient that plants need for growth, and maintaining natural soil fertility, for millions of years. Nostoc is present in soils everywhere – even in some deserts – but occasionally, during spells of wet weather, it proliferates inside a mucilaginous matrix and forms great convoluted balls of slime (bottom photo) that can cover large areas of bog, wet grass or soil. In that state it’s incredibly slippery: step on it and you’re likely to fall flat on your back.
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REMEDIES FOR HEADACHE


Headache is a common problem, specially among the working crowd. Headache is caused due to several factors, but we can put it under three broad categories - 

1.Tension – This is the most common cause of headache. Tension creates a spasm of the muscles at the back of the neck. The muscle spasm gets the tissues over the surface of the cranium and thus, the pain is felt not only on in the neck but also on the forehead.

2.Migraine – Migraine is the abnormality of the nervous system. This strain on the nervous system is caused due to eye strain, shock, stomach disorders etc. Migraine is a chronic disease which needs medical attention.

3.Cluster Headache – Cluster headaches are repetitive and gets back several times in a month. These are generally caused due to constant pressure on the nerves like alcohol consumption, chain smoking etc. 

Headaches are very disturbing and restricts your attention to the pain alone. At this moment pain killer seems to be the only solution to get relief form headache. Pain killers, however, have side effects. Here are few home remedies to get relief from headache - 

1.For chronic headache, eat sliced apple with salt everyday in the morning for a week.

2.Crush lemon crust into a fine powder and make it into a paste with the use of water. Apply this on the forehead. This is quick relief form headache caused due to tension.

3.Apply a small amount of Eucalyptus oil on the center of the head and cover it with a towel dipped in warm water. This is one of the most effective ways of curing pain.

4.Put 3 drops of ghee in your nostrils for a week to get rid of headache from cold. 

5.Drink a glass of water with a teaspoon of honey every morning to treat chronic headache. 

6.Grind watermelon seeds with poppy seeds and consume three grams of it everyday if you are suffering constant pain.

7.Application of sandalwood paste on the forehead is one of the tradition ways of curing headache. 

These seven tips will surely give you quick relief from headache and does not have any side effects. They not only get you relief from headache but also treats it, so that you dont suffer the symptoms again.
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Myth! Eye Wrinkles

Myth! Eye Wrinkles

Myth! Eye Wrinkles
Myth! Eye Wrinkles


Myth! Eye Wrinkles- Wrinkles on the face can lose confidence for some women. Moreover, when the new woman in their 20s with a myriad of activities. Premature aging may spoil the mood of work and a date with her lover or friend dekat.Yuks find some myths about wrinkles, and we can know what we should do to combat premature aging:

1. Wrinkles only happen when we are old

Myth of the above is not the entirely true, in the general, the symptoms of the aging process begins at the age of 25s, a decrease in skin elasticity and kolegen. However, a healthy lifestyle and skin care routine can prevent the signs of aging so that wrinkles will appear at an older age. 

2. Asian skin early wrinkles than white people

Not true, it is actually a Caucasian skin that is prone to wrinkles in the skin of Asian people. This is because the structure of the Asian skin tends to be thick and oily. Indeed, people in Asia are mostly tropical climate and exposed to ultraviolet light more. But fortunately, tropical humidity is also high enough so that our skin is more moisture. 

3.Sleep stomach can cause wrinkles

It was true that the wrong posisis sleep can also lead to the formation of skin wrinkles. If you often sleep on his side or stomach, the risk of  appearance of wrinkles on the face will be greater because of friction and gravity. So you should sleep with the supine position. 

4.Wrinkless more experienced by people who diet and skinny

It is true that the wrong diet can lead to lack of nutrition, and may be associated with the occurrence of wrinkles on the skin. Reduced the nutrient intake caused a decline in the levels of vitamins and minerals are absorbed by the body so that the immune system also come down. Though these substances are responsible panuh in the process of replacement of damaged skin cells and can maintain skin elasticity and moisture. So, multiply the consumption of foods and fruits that contain antioxidants and vitamin C.  Myth! Eye Wrinkles

5.Wrinkless the descent

This myth is true that genetic factors also play a role in the formation of wrinkles. If in your family there are members who have wrinkles around the eyes and skin also tends to be dry, so you will be able to have the same condition.

6.Work field wrinkle prone than office workers

Both of these types of jobs is a high risk, but it does not mean the field workers are at higher risk. Sun exposure is not good for the skin but are in air-conditioned room can make dry skin and lead to wrinkles. Therefore, sunscreen and moisturizers for field workers to office workers is mandatory items.

7.The Beszt removes wrinkles with Botox

This is not true, carefully choosing your skin care methods that wrinkles. Although today many are almost instantaneous. Should first identify the type of wrinkles that you experienced and adjust with your age. As for superficial wrinkles, overcome with antiaging cream. For this type of  the deeper wrinkles, peels chemical and microdermabrasion method could be an option. Botox and surgery surgical methods can the turn your skin, but  procedure also has indications and higher consequences. Before you use it make sure you consult your physician first.

8.Wrinkless not influenced by the hormone, but were influenced by the moisture content of the skin

Wrinkles are influenced by several hormones in our bodies. Especially kortiso usual hormone produced can make stress. The decline in estrogen also affects the onset of wrinkles on the faces of the women. In the male hormone testosterone also play a role in triggering wrinkles on the skin, but not for  influence of the female hormone estrogen.

9.calisthenics  face and laugh prevent wrinkles

Laughter does have many good effects for the body as well as ageless and immune enhancement. But too expressive when laughter can cause excessive facial muscles move. If accompanied by a thinning of the skin because it will surely make indentations called mechanical wrinkles that often occur in the forehead and eyes.
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More Grey Hairs


I seem to be acquiring more grey hairs with every passing day at the moment, so I thought I might as well take a look at them under the microscope. Magnfied x400, its clear that the grey ones arent so much grey as colourless (foreground) - increasing numbers of my hair follicles have given up making melanin pigment.
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Neuromuscular Dynamics of Octopus Arm Movements

I was planning on writing an article about cephalopod statocysts (and I still am; Ive just had trouble deciding which pieces of research I want to cover and which I want to leave out) to continue on the theme of cephalopod sensory systems.  Ive stumbled upon a line research that I just had to blog about, though, so Im putting off the statocyst post even further.  The research in question is a series of studies by The Octopus Group at the Hebrew University of Jerusalem on the biomechanics and neural control of reaching movements of octopuses.  I read this research some months ago (before I was blogging,) and I was reminded of it while watching Twister (the resident E. dofleini at the Niagara Falls Aquarium) groping about in his enclosure.  I noticed that, as he moved his arms about, the movements almost always started with a bend near the base of the arm, which traveled out to the tip, becoming sharper and moving faster as it proceeded.  It looked for all the world like the way a wave travels through water (or, more geek-ily, the way one imagines spontaneous activity propagating in a spatially extended nervous system.)  The series of studies I will talk about here shows that this is generally the case, and characterizes the way that this happens with some detail, although we still do not know this system in nearly as fine detail as we know the vertebrate neuro-muscular system.  Im getting ahead of myself, though.

Why do we care about the details of how octopuses move their arms?  First, its just plain cool - who, upon looking at an octopus moving, hasnt wondered how it can possibly keep track of all those arms?  Second, the octopus arm provides a unique model nervous system for a few reasons.  It is a muscular hydrostat - that it, having no bones, it is a system of muscles that run perpendicularly to each other that maintain a roughly constant total volume; this property of an octopus arm allows it to function like a very flexible vertebrate limb because the muscles can pull against each other to form temporary, semi-rigid structures that allow the arms to bear weight.  As such, it is a novel motor system (in terms of research, that is,) with most of the well-characterized motor systems we know of (ie. human, primate, reptile, etc.) are composed of skeletal muscles, which pull against bones.  Besides this, the task of coordinating the movement of eight almost infinitely flexible arms is a herculean task in terms of neural processing, and it would be very informative (as well as a triumph of systems neuroscience) to understand how this is done.  It has been thought, since the early days of octopus neuroanatomy, that much of the movement of the octopuss arms (and probably those of other cephalopods) is encoded in the nervous system of the arms rather than in the central nervous system (Graziadei, 1971).  This is evidenced by the fact that there is no straightforward representation of the arms in the brain of the octopus, as there is in humans and most other vertebrates, as far as we know, and so it is unlikely that fine motor control comes from the central nervous system.  Supporting the importance of the distributed nervous system of the arms is its incredible scale: the nervous system of the arms is much larger than the central nervous system of octopus, containing around 2/3 of all of the neurons in the animal.  The octopus arm, then, is a unique example of a highly complex, distributed motor system that stands in contrast to the centrally controlled motor systems we are most familiar with.  As with almost every topic in comparative neuroscience (Im a big sucker for it), I think that the octopus motor system is important because by understanding it, we will understand more about vertebrate nervous systems; that is, we will (pretending for a moment that we could actually solve both systems) understand which features of them are critically related to the specifics of vertebrate and invertebrate neural functioning, physiology, development, and ecology.  We would come closer to understanding why each system evolved the way it evolved.  Finally, we would exercise our tools of modeling neural computation in a way that would allow us to figure out how generalizable they are.  My final verdict: this is a good thing to study.

So now youre bored.  You want to hear about some research!  Well, I wont disappoint; at least, I hope I wont.  Well start with Gutfreund et al. (1998), one of the early papers out of this research group, which kicked off this line of research by examining the neuromuscular dynamics of octopus reaching movements.  I should note that (presumably for simplicity,) this group generally only studies reaching movements in a single arm - it is not know exactly how their findings might relate to more complicated movements, including those involving multiple arms.  As a disclaimer I am going to leave out description of a large portion of their study, which I encourage you to read in full, for my own convenience, and only present the results that I think are most relevant to the topic at hand.

This authors in this study used electromyography (a method of measuring the electrical activity of muscles) in O. vulgaris to determine how arm muscles are activated in sequence to produce octopus reaching movements.  Briefly, they put electrodes through two points in a single arm of their (anesthetized) test animals, then allowed the animals to wake up and elicited reaching movements by tempting the octopus with either a crab or a target that was associated with food.  They videotaped the reaching movement, which allowed them to compare the electromyogram to the behavior of the octopus.  Reproduced below is their first figure, showing the gross cross-sectional anatomy of the octopus arm, as well as their electrode placement:

The white arrows indicate the position of the electrode, which is the white line running through the muscle.  The striated outer portions of the arm are the muscle, and the round shape in the middle is the nerve cord of the arm.

They found that reaching arm movements usually start with a sharp bend near the base of the arm, which travels outwards until it reaches the tip, accelerating somewhat throughout the extention and then slowing as the arm reaches its target.  Heres a series of images showing the behavior:
 

The authors found that this type of arm extension occurs virtue of a propagating wave of muscle contraction traveling down the arm, from the base to the tip.  Shown here are examples of the type of data they used to confirm this:

The left panel shows two electromyograms from a single trial, the top one from the electrode nearer to the arm tip, and the bottom one nearer to the base of the arm.  The arrows indicate when the bend in the arm reached each electrode.  As is apparent, neuromuscular activity at the proximal site started earlier than that at the distal site, coinciding approximately with the timing of the movement of the bend in the octopuses arm.  The graph shows the correlation between the lag in the electromyogram record between the two sites and the time it took for the bend in the arm to move between the two sites.  Its clear that the propagation of the wave of electrical activity down the arm is highly correlated with the motion of the arm.  The authors continue on to characterize some of the properties of these arm movements in more detail and propose a mathematical model for the movement of the octopus arm, but Ill leave those results out, here.  I recommend this article for its methodological clarity - too seldom do authors take such pains to make their method so clear and so thoroughly address their research question.

Moving on, the same reearch group (with a different first author) published a paper in Science describing their experiments with isolated arm preparations (Sumbre et al. 2001).  This is where it gets really interesting to me, because this experiment really gets at the distinction between central and peripheral motor control.  The authors made their preparations by either denervating one arm of an octopus that had already been decerebrated (a procedure somewhat akin to an octopus lobotomy) by severing its connection to the brain, or by severing an arm completely.  They then attached the base of the arm to a surface, and stimulated the nerve cord at the base of the arm.  It was found that, in a large percentage of cases (46%, to be exact,) the movement resembled the reaching movement seen in an intact animal.  The figure below (taken from the paper) shows the reaching movement of a normal animal (on the left) and that elicited by stimulating the nerve cord of a denervated arm in a decerebrate animal:


Importantly (for reasons Ill explain in a second,) it appears that the arm movements were initiated, but not sustained by the stimulation.  We can tell the difference because the "reaching" movement continued through to completion even when it began slightly after the experimenters stopped stimulating the arm.  This shows that the brief stimulation started a motor process that was maintained by the intrinsic neuromuscular system of the arm.  The authors also found that similar movements could be elicited in amputated arms by "tactile stimulation of the skin or suckers."  After a brief analysis of the kinetics of the evoked movements, the authors conclude that they, like those of intact animals, are caused by a propagation of muscle activity down the arm.

The authors conclusion:

          "The division between the central and
          peripheral levels of the octopus motor control
          system resembles the hierarchical organization
          of motor control systems in other
          invertebrates and vertebrates, even
          though in the octopus it uniquely serves as
          an important component in a goal-directed
          voluntary movement rather than in rhythmical
          or reflexive behaviors."

The peripheral nervous system of the octopus appears to play a much greater role in the programming of movement that does the peripheral nervous system of vertebrates (which can only independently control simple reflexes and some other involuntary movements like peristalsis), even to the extent that it can execute complex movements (like reaching as if to grasp) all by itself.  That propagating wave of muscle activity isnt coordinated by the central nervous system, like coordinated movements are in humans; rather, its coordinated by the nervous system intrinsic to each arm.  This is convenient for the octopus because it means that it generally does not need to keep track of its arms (that is, its central nervous system doesnt have to spend a lot of resources monitoring and controlling them) because they largely take care of themselves.  Its a good solution to the problem of having a large number of incredibly flexible appendages.

The exact extent of the arms abilities to coordinate their own motor activity, as well as activity between arms, remains to be uncovered by more and more detailed experiments on a variety of types of movement, but the general conclusion seems pretty solid to me, and fits nicely with what we know about the neuroanatomy of the octopus.  It would also be interesting to see the results of similar studies in other cephalopods.  I have a sneaking suspicion that one could relate the extent of the peripheral nervous systems "motor autonomy" from the central nervous system to the complexity of arm movement required by a given species lifestyle.  It would be a neat idea to explore (if I had a laboratory on the Italian coast and a million-dollar grant to study squids.  I can dream, right?)

Theres one more article I wanted to cover here, but I dont have time at the moment, and I want to get this up tonight.  Its by the same group, and it applies what the previous studies showed to explain the way that octopuses retract their arms after they have grasped their target.  Hopefully Ill have a shorter post on that before the end of the weekend.

As always, thanks for reading!

ResearchBlogging.org
Sumbre, G. (2001). Control of Octopus Arm Extension by a Peripheral Motor Program Science, 293 (5536), 1845-1848 DOI: 10.1126/science.1060976


Gutfreund Y, Flash T, Fiorito G, & Hochner B (1998). Patterns of arm muscle activation involved in octopus reaching movements. The Journal of neuroscience : the official journal of the Society for Neuroscience, 18 (15), 5976-87 PMID: 9671683

Graziadei, P.P.C. (1971). The nervous system of the arms. pp. 44-61 in Young, J.Z. The Anatomy of the Nervous System of Octopus vulgaris. Oxford : Clarendon Press.
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Kidneys What is the function of the Kidneys

The kidney filters body fluids within the nephron units and expels wastes via the ureter.

Kidney is one of a pair of organs located at the back of the abdomen, against the strong muscles next to the spine, and behind the intestines and other organs.
The adrenal glands lie on top of the kidneys.
Each kidney weighs about 5 ounces (140g) and is about 4 inches (10cm) long in the average adult.
Its inner structure, which is called the renal pelvis, collects urine as it is formed and passes it out of the kidney to the bladder via the ureter.
The renal pelvis also is connected to the artery and vein that carry blood to and from the kidney.

What is the function of the Kidneys?

The kidneys filter out water and also unwanted substances in the blood.
These substances are produced by the normal working of the body.
They are excreted by the kidneys in the form of urine.
The kidneys also keep the salts and water of the body in correct balance.

How do kidneys work?

The blood passes through each kidney under high pressure.
The blood is filtered by the glomeruli, special structures in the kidney containing clusters of capillaries that collect water, salts, and unwanted substances.
The filtrate passes along a fine tube, the nephron (of which there are approximately one million in each kidney), which reabsorbs any of the water, glucose, and salts that the body still re-quires and allows the rest to pass into the pelvis of the kidney as urine.
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Eros and Psyche Greek Mythology

According to Hesiods Theogony, Eros, the divine spirit of Love, sprang forth from Chaos, while all was still in confusion, and by his beneficent power reduced to order and harmony the shapeless, conflicting elements, which, under his influence, began to assume distinct forms. This ancient Eros is represented as a full-grown and very beautiful youth, crowned with flowers, and leaning on a shepherds crook.
In the course of time, this beautiful conception gradually faded away, and though occasional mention still continues to be made of the Eros of Chaos, he is replaced by the son of Aphrodite, the popular, mischief-loving little god of Love, so familiar to us all.
In one of the myths concerning Eros, Aphrodite is described as complaining to Themis, that her son, though so beautiful, did not appear to increase in stature; whereupon Themis suggested that his small proportions were probably attributable to the fact of his being always alone, and advised his mother to let him have a companion. Aphrodite accordingly gave him, as a playfellow, his younger brother Anteros (requited love), and soon had the gratification of seeing the little Eros begin to grow and thrive; but, curious to relate, this desirable result only continued as long as the brothers remained together, for the moment they were separated, Eros shrank once more to his original size.
By degrees the conception of Eros became multiplied and we hear of little love-gods (Amors), who appear under the most charming and diversified forms. These love-gods, who afforded to artists inexhaustible subjects for the exercise of their imagination, are represented as being engaged in various occupations, such as hunting, fishing, rowing, driving chariots, and even busying themselves in mechanical labour.

Eros and Psyche

Perhaps no myth is more charming and interesting than that of Eros and Psyche, which is as follows:—Psyche, the youngest of three princesses, was so transcendently beautiful that Aphrodite herself became jealous of her, and no mortal dared to aspire to the honour of her hand. As her sisters, who were by no means equal to her in attractions, were married, and Psyche still remained unwedded, her father consulted the oracle of Delphi, and, in obedience to the divine response, caused her to be dressed as though for the grave, and conducted to the edge of a yawning precipice. No sooner was she alone than she felt herself lifted up, and wafted away by the gentle west wind Zephyrus, who transported her to a verdant meadow, in the midst of which stood a stately palace, surrounded by groves and fountains.
Here dwelt Eros, the god of Love, in whose arms Zephyrus deposited his lovely burden. Eros, himself unseen, wooed her in the softest accents of affection; but warned her, as she valued his love, not to endeavour to behold his form. For some time Psyche was obedient to the injunction of her immortal spouse, and made no effort to gratify her natural curiosity; but, unfortunately, in the midst of her happiness she was seized with an unconquerable longing for the society of her sisters, and, in accordance with her desire, they were conducted by Zephyrus to her fairy-like abode. Filled with envy at the sight of her felicity, they poisoned her mind against her husband, and telling her that her unseen lover was a frightful monster, they gave her a sharp dagger, which they persuaded her to use for the purpose of delivering herself from his power.

After the departure of her sisters, Psyche resolved to take the first opportunity of following their malicious counsel. She accordingly rose in the dead of night, and taking a lamp in one hand and a dagger in the other, stealthily approached the couch where Eros was reposing, when, instead of the frightful monster she had expected to see, the beauteous form of the god of Love greeted her view. Overcome with surprise and admiration, Psyche stooped down to gaze more closely on his lovely features, when, from the lamp which she held in her trembling hand, there fell a drop of burning oil upon the shoulder of the sleeping god, who instantly awoke, and seeing Psyche standing over him with the instrument of death in her hand, sorrowfully reproached her for her treacherous designs, and, spreading out his wings, flew away.
In despair at having lost her lover, the unhappy Psyche endeavoured to put an end to her existence by throwing herself into the nearest river; but instead of closing over her, the waters bore her gently to the opposite bank, where Pan (the god of shepherds) received her, and consoled her with the hope of becoming eventually reconciled to her husband.
Meanwhile her wicked sisters, in expectation of meeting with the same good fortune which had befallen Psyche, placed themselves on the edge of the rock, but were both precipitated into the chasm below.
Psyche herself, filled with a restless yearning for her lost love, wandered all over the world in search of him. At length she appealed to Aphrodite to take compassion on her; but the goddess of Beauty, still jealous of her charms, imposed upon her the hardest tasks, the accomplishment of which often appeared impossible. In these [153]she was always assisted by invisible, beneficent beings, sent to her by Eros, who still loved her, and continued to watch over her welfare.
Eros
Psyche had to undergo a long and severe penance before she became worthy to regain the happiness, which she had so foolishly trifled away. At last Aphrodite commanded her to descend into the under world, and obtain from Persephone a box containing all the charms of beauty. Psyches courage now failed her, for she concluded that death must of necessity precede her entrance into the realm of shades. About to abandon herself to despair, she heard a voice which warned her of every danger to be avoided on her perilous journey, and instructed her with regard to certain precautions to be observed. These were as follows:—not to omit to provide herself with the ferrymans toll for Charon, and the cake to pacify Cerberus, also to refrain from taking any part in the banquets of Aïdes and Persephone, and, above all things, to bring the box of beauty charms unopened to Aphrodite. In conclusion, the voice assured her, that compliance with the above conditions would insure for her a safe return to the realms of light. But, alas, Psyche, who had implicitly followed all injunctions, could not withstand the temptation of the last condition; and, hardly had she quitted the lower world, when, unable to resist the curiosity which devoured her, she raised the lid of the box with eager expectation. But, instead of the wondrous charms of beauty which she expected to behold, there issued from the casket a dense black vapour, which had the effect of throwing her into a death-like sleep, out of which Eros, who had long hovered round her unseen, at length awoke her with the point of one of his golden arrows. He gently reproached her with this second proof of her curiosity and folly, and then, having persuaded Aphrodite to be reconciled to his beloved, he induced Zeus to admit her among the immortal gods.
Their reunion was celebrated amidst the rejoicings of all the Olympian deities. The Graces shed perfume on their path, the Hours sprinkled roses over the sky, Apollo added the music of his lyre, and the Muses united their voices in a glad chorus of delight.
This myth would appear to be an allegory, which signifies that the soul, before it can be reunited to its original divine essence, must be purified by the chastening sorrows and sufferings of its earthly career.
Eros is represented as a lovely boy, with rounded limbs, and a merry, roguish expression. He has golden wings, and a quiver slung over his shoulder, which contained his magical and unerring arrows; in one hand he bears his golden bow, and in the other a torch.
He is also frequently depicted riding on a lion, dolphin, or eagle, or seated in a chariot drawn by stags or wild boars, undoubtedly emblematical of the power of love as the subduer of all nature, even of the wild animals.
In Rome, Eros was worshipped under the name of Amor or Cupid.


Text:
Myths and Legends of Ancient Greece and Rome
Author: E.M. Berens
Published: 1880

The Project Gutenberg EBook
Produced by Alicia Williams, Keith Edkins and the Online
Distributed Proofreading Team at http://www.pgdp.net
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Amber eye colour twilight for real

Amber eye colour in humans

Have you ever heard of the amber eye colour? Do you know what it is? Only a small number of people know someone with these extremely special eye colour. Around the world, only less then 1% has the amber eye colour. Amber eyes may even be the rarest eye colour in the world!
 

The pigment responsible for the amber colour is lipochrome. This yellowish pigment also exist in green eyes. The amber eye colour has a lot of this yellow lipochrome but a low amount of melanin. Sometimes, when the light shines on the iris, amber eyes shines like two golden coins. This light scattering is called rayleigh scattering. 

Amber Eyes


Amber or Hazel eyes?

Sometimes people confuse amber with hazel eyes. Amber eyes are of a solid uniform colour. The color can shift some due light effects, but the overall colour is the same. Hazel eyes tend to be more multicolourish. They can have green, brown and some golden/red flecks in it.

Read More: Ambercoloured eyes are amazing!
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THANK YOU! 2

Thank you people from RUSSIA, INDIA and NORTH AMERICA (Its very surprising even after criticising capitalism every now and then, most of my audience is from USA.) I KNOW, GOOD PEOPLE FROM USA REALISE, THAT CAPITALISM HARMS US,THIRD WORLD COUNTRIES. THANK YOU FOR REALISING. Thanks for viewing my blog. Keep enjoying. Keep helping.
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Sankata Nashana Ganapathi Stotram With English Lyrics Happy Ganesh Chaturthi

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waheguru simran soft soothing shabad

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Hormone definition for kids What are Hormones

Are you tall for your age, or short?
How tall you grow depends mostly on chemical substances called hormones, which move around your body in your blood.
Some hormones cause the cells in your body to make more protein. They then make the cells grow and divide, so that all of your body gets bigger.
Because hormones are going around in your blood, they reach every cell in your body. So all your cells grow and divide at your normal rate.
Can you imagine how it would be if some-parts of your body grew faster than others? 
This is why hormones are so important.

Hormones control the different parts of your body, so that everything is regulated. Hormones are regulators of chemical and growth activity in the body.

A special kind of hormone, called growth hormone, helps the long bones to grow. Children who do not produce enough of this hormone may not grow as tall as they would be able to grow with the hormone.
The balance of hormones in your blood is controlled by the pituitary gland, which lies just below the brain.
The pituitary gland produces hormones which control many of the body’s activities.
Large numbers of nerve cells and blood vessels link the pituitary gland to a part of the brain called the hypothalamus. The hypothalamus controls the pituitary gland by sending “on” and “off ” messages through the nerve cells and the bloodstream.
These messages affect the pituitary gland with regard to the releasing of its hormones.

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Tuesday, March 17, 2015

Anatomy of the Human Eye

Anatomy of the Human Eye

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Cheetahs


Cheetah factsCheetahs
Learn more about the cheetah by reading these fun cheetah facts. 
Cheetahs are part of the big cat family and while they can’t climb
trees, they can run faster than any other land animal. Read on for 
more interesting cheetah information.
  • The cheetah is the fastest land animal in the world. They can reach a top speed of around 113 km per hour.
  • A cheetah can accelerate from 0 to 113 km in just a few seconds.
  • Cheetahs are extremely fast however they tire quickly and can only keep up their top speed for a few minutes before they are too tired to continue.
  • Cheetahs are smaller than other members of the big cat family, weighing only 45 – 60 kilograms.
  • One way to always recognise a cheetah is by the long, black lines which run from the inside of each eye to the mouth. These are usually called “tear lines” and scientists believe they help protect the cheetah’s eyes from the harsh sun and help them to see long distances.
  • Cheetahs are the only big cat that cannot roar. The can purr though and usually purr most loudly when they are grooming or sitting near other cheetahs.
  • While lions and leopards usually do their hunting at night, cheetahs hunt for food during the day.
  • A cheetah has amazing eyesight during the day and can spot prey from 5 km away.
  • Cheetahs cannot climb trees and have poor night vision. 
  • With their light body weight and blunt claws, cheetahs are not well designed to protect themselves or their prey. When a larger or more aggressive animal approaches a cheetah in the wild, it will give up its catch to avoid a fight.
  • Cheetahs only need to drink once every three to four days.




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Sophies Squash

I love, love, love this picture book. Perfect for the fall season, Sophies Squash tells of an abiding friendship that forms between a young girl and her, well, gourd. Sophie spots an appealingly shaped butternut squash at a farmers market and by the time suppertime rolls around, shes named her new acquaintance Bernice and given her a face with markers. Her mother, who is shown thumbing through a cookbook looking for squash recipes, says, "Ill call for a pizza."

If the mother thinks her daughter will tire of her new friend, shes mistaken. Sophie and Bernice enjoy idyllic fall days playing together. When Bernice develops some spots, Sophie, undeterred, calls them freckles. But soon even Sophie cant deny that her friend isnt her usual self. "Bernice seemed softer, and her somersaults lacked their usual style."

On advice from a farmer, Sophie tucks her friend into "a bed of soft soil" to recover. And recover she does, and come summer Sophie has two new friends that are "just the right size to love."

Pitch perfect and with exquisite pacing, this book is sure to charm young readers. I only wish it was around when my daughter was a first grader. Thats when she created--without any help--a sister doll from a rolled-up sleeping bag, tee shirt, hat, and a pasted-on face. Thats why I wasnt surprise to learn that first time author Pat Zietlow Miller based the story on her daughter, who, like Sophie, met a squash she couldnt resist.

Anne Wilsdorfs illustrations are endearing and full of life. Her Sophie looks just the type of girl who would tenderly bounce a squash on her knee or cuddle it in her arms.  

Highly recommended!

Sophies Squash
By Pat Zietlow Miller
Illustrations by Anne Wilsdorf
Schwartz & Wade Books
Published: 2013
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Top Ten Books I Just Had to Buy But Are Still Sitting on My Bookshelf



Well, this weeks Top Ten Tuesday list by The Broke and the Bookish was ridiculously easy. All I had to do was scoot over to my bookcase and pick up the row of books Ive been meaning to read and never have...and if Im truthful, most likely never will. Sigh.

Here they are, in alphabetical order by authors last name.

1. Herbert Rowbarge by Natalie Babbitt. I bought the paperback edition sometimes in the 80s and it has moved from bookshelf to bookshelf from apartment to house to apartment to house to house. I bought it because I loved Natalie Babbitss outstanding childrens novel Tuck Everlasting. But for some reason I have never cracked this one open so I cant even say what its about. I keep it because Ive had it so long. Silly reason, I know.
2. Arthur & George by Julian Barnes. I love detective fiction and I love Victorian settings. After seeing many good reviews, I snatched up a copy, which remains unread.
3. Possession by A. S. Byatt. This one is not actually on my bookshelf. Somehow I ended up with two hardcover copies, and after years of them both sitting reproachfully on my shelf, I finally donated them to a library. I did start the novel and did not like it. The Childrens Hour, her latest, has gotten rave reviews. I may give it a try, but a library copy this time.
4. Madame Bovary by Gustave Flaubert. Dont remember how I even came to own this one. Its a classic and I really should read it, I know. But there it sits on the shelf.
5. The Graveyard Book by Neil Gaiman. Bought the hardcover edition after it won the Newbery Award. Again, right up my alley as I love ghosts, graveyards, etc. This one, though, I swear I will read--and soon.
6. Freddy and Frederick by Mark Helprin. Bought this at a used bookstore for one dollar. According to the jacket flap, its a funny allegory about fictional members of the British royal family. But its more than 500 pages long!
7. The Remains of the Day by Kazuo Ishiguro. Another one Ive had for years. I think I started it once, then put it down. Maybe Ill watch the movie.
8. The Portrait of a Lady by Henry James. I know, I know; its a classic. But Im not a fan of Henry James. This novel is supposed to be one of his more accessible ones. I started it, but it was a snore. Sorry, Henry James fans.
9. Angelas Ashes by Frank McCourt. Everyone has read this memoir, even people who are not particularly bookish. Except me. I know I would like it, too. So why does it remain unread? I think because when everyone was busy reading it, I wasnt. Now it feels like I missed the bus.
10. Atonement and Saturday by Ian McEwan. Yes, not one, but two of his novels sit on my shelf, unread. Both books have interesting subjects and good reviews. They just didnt click with me.

So theres my shameful list. What untouched books sit on your shelves? Confess!
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Swot Diagram Template


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Ling Ting

Grace Lin, author of numerous picture books as well as three middle-grade novels, writes and illustrates her first early reader about a pair of identical twins who are most definitely not exactly alike.



One of my childhood friends wished she could have been born a twin.  I could never understand her strange desire. Why would I want there to be two of me, someone else who exactly like me? This concern doesnt matter one whit to Lins characters, Ling and Ting, who are confident about their individuality. 

In the first story, Ling sits patiently as her hair is trimmed. Ting is fidgety. She twists and turns in her seat. Then an inopportune sneeze guarantees that shell look different than her sister and she ends up with a giant gap in her bangs. (In a nice detail the art shows a bandage on Tings knee, indicating that shes accident-prone.)

There are six stories in all, and each one showcases Ling and Tings individuality and unique ways of reacting to events. The girls dabble in magic tricks, make dumplings (Lings are smooth ones, Tings fat), eat them (Ting with chopsticks, Ling with a fork), and visit the library. In the final chapter Ting tells Ling a story in which she cleverly incorporates--and mixes up--all the books previous events. 

An early reader doesnt need to be a twin to enjoy this book. She just needs to be one-of-a-kind, like Ling and Ting.
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What is the Volume of Your Lungs

What  is the volume of your lungs?


What youll need:
  • Clean plastic tubing
  • A large plastic bottle
  • Water
  • Kitchen sink or large water basin
 

Instructions:
  1. Make sure the plastic tubing is clean
  2. Put about 10cm of water into your kitchen sink.
  3. Fill the plastic bottle right to the top with water.
  4. Put your hand over the top of the bottle to stop water escaping when you turn it upside down.
  5. Turn the bottle upside down. Place the top of the bottle under the water in the sink before removing your hand.
  6. Push one end of the plastic tube into the bottle.
  7. Take a big breath in.
  8. Breathe out as much air as you can through the tube.
  9. Measure the volume of air your lungs had in them.
  10. Make sure you clean up the area to finish.
Whats happening?
As you breathe out through the tube, the air from your lungs takes the place of the water in the bottle. If you made sure you took a big breath in and breathed out fully then the resulting volume of water you pushed out is equivalent to how much air your lungs can hold. Having a big air capacity in your lungs means you can distribute oxygen around your body at a faster rate. The air capacity of lungs (or VO2 max) increases naturally as children grow up but can also be increased with regular exercise.
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Electrical Circuit Design with VeSys Wiring design software


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Monday, March 16, 2015

Layers of Epidermis Skin

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BACTERIAL INFECTION

IMPETIGO

INTRODUCTION

  • Contagious superficial Pyogenic infection of the skin.


Two main clinical form are
  • Non – Bullous impetigo ( or Impetigo contagiosa of Tilbury Fox)

Causative organism – Staph. aureus, Streptococcus or both

  • Bullous Impetigo

Causative organism – Mainly Staph disease but rarely can be due to streptococci


Pathology 

Bullous impetigo 

  • Epidermis split just below the granular layer to form large blister


  • Neutrophils migrate through spongiotic epidermis to blisters cavity, which may also contain bacilli


  • Occasionally acanthotic cells may be seen


  • Dermis contains inflammatory infiltrate of Neutrophils and lymphocytes



Non – Bullous impetigo

  • Histology is similar except that blister formation is slight and transient 



Clinical Feature

  • In non-bullous impetigo, the initial lesion is a very thin-walled vesicle on an erythematous base. 
  • The vesicle ruptures so rapidly that it is seldom seen as such.
  • The exuding serum dries to form yellowish brown crusts.
  • The crusts eventually dry and separate to leave erythema, which fades without scarring.
  • The face, especially around the nose and mouth, and the limbs are the sites most commonly affected,



Non-bullous impetigo

  • In bullous impetigo, the bullae are less rapidly ruptured and become much larger;, and persist for 2 or 3 days.
  • After rupture thin, flat, brownish crusts are formed. Central healing and peripheral extension may give rise to circinate lesions.


  • Although the face is often affected, the lesions may occur anywhere.



Bullous impetigo
Treatment

  • Topical:

    Mupirocin or fusidic acid is active against both    organism.
    Washing with soap and water.
  • Oral:

    Antibiotics like Flucloxacillin or Erythromycinin severe cases.
  • Proper education


Complication 

  • Infective complication are uncommon in the absence of systemic disease or malnutrition


  • Cellulitis occasionally follow streptococcal disease


  • Post streptococcal glomerulonephritis 

Specially following S. pyogens infection

  • Scarlet fever, Urticaria and Erythema multiforme



Ecthyma 

Introduction 

Pyogenic infection of the skin characterized by the formation of adherent crusts, beneath which ulceration occur.

Aetiology 

Bacteriological status – Similar to Impetigo

  • Predisposing factors 

Poor hygiene 
Malnutrition 
Minor injuries 
Other skin condition, like scabies
IV drug abusers

Clinical Feature 

  • Small bullae or pustules on an erythematous base


  • Soon surmounted by hard crust of dried exudate, which increase in size by peripheral accretion.


  • The base may become indurated and a red edematous areola is often present.


  • Crust is removed with difficulty , to reveal a purulent irregular scar.




Ecthyema enduratum of Bazin


  • Healing occur after few weeks, with scarring


  • Common sites 

Buttocks, Thighs and Legs


Treatment 

  • Antibiotics active against both staph. and streptococcus


  • Improve hygiene and nutrition 


  • Topical therapy either with sulconazole or miconazole clears lesions satisfactorily over 1 week.


  • Treatment of underlying disease – e.g.. Scabies



Erythrasma

  • Erythrasma is a mild, chronic, localized superficial infection of the skin caused by bacteria, known as C. minutissimum.


  • Clinical infection may occur at any age but is more common among adults than children.


  • Detected by Wood’s light examination- pink fluorescence


Clinical features

  • Asymptomatic or mild itch.


  • Erythrasma involves the toe clefts more frequently than any other site. 


  • As clinically manifest lesions it occurs most commonly in the groins, axillae and the intergluteal and submammary flexures. 





Treatment

  • Topical azole cream- cotrimazole, miconazole.
  • Topical antibiotics
  • Extensive cases: oral erythromycin

Cellulitis and Erysipelas 

Introduction 

  • Cellulitis is an inflammation of subcutaneous tissue which is usually infective.

  • Erysipelas is a bacterial infection of the dermis and upper subcutaneous tissue
  • Well defined, raised edge, reflecting more superficial (dermal) involvement (clinical hallmark)
  • It can sometime penetrate deep dermis and subcutaneous tissue to form cellulitis.

Bacteriology 

Group A beta hemolytic streptococci most of the time

Other organisms 
Group C or G streptococci
Group B streptococci in new borne
Staph aureus 



Predisposing factors:
DM
Vericose leg ulcer
        Tinea pedis

Clinical Features 


Erythema, heat swelling and pain.
In erysipelas, the edge of the lesion is well-demarcated and raised, but in cellulitis it is diffuse.
Blistering occur in both conditions.
Site
Cellulitis:
Legs
Erysipelas:
Lower extremities 
Face  - may spread to eyelids but orbital complications are rare



Cellulitis



Erysipelas

Dx

  • Specimens for bacteriological examination should be
  • taken from vesicle fluid or eroded or ulcerated surfaces, in addition to blood cultures.

Treatment
  • Antistreptococcal agent:
Phenoxymethylpenicillin
Erythromycin/ciprofloxacin- in case of penicillin sensitivity
          I.V antibiotics- in severe cases.

Folliculitis

Circumscribed infectious process that originate in the hair follicle and is defined by its anatomic features.

Mainly of two types
Superficial 
Located superficially

Deep 
It extend more deeply to produce perifollicular inflammation

Superficial folliculitis 
  • Subacute or chronic inflammation confined to ostium or extend slightly below it
  • Common condition which heals without scarring



Common causes

  • Staphylococcus auerus and coagulase negative staph


Physical 
  • Traumatic epilation
  • Adhesive plaster and dressing


Chemical injury 
  • Contact with mineral oils
  • Exposure to tar products
Sites 

  • Commom in children and common sites being scalp and limbs.


Lesion 

  • Present as small follicular papules or pin head pustules, which are rarely painful


  • Pus culture is sterile most of time and rarely coagulase negative staph can be isolated




Follicular impetigo of Bockhart

  • Variant of superficial folliculitis caused by staph. aureus 

  • Common in childhood age

Treatment 

  • Removal of causative agent in case of physical and chemical factors suspected

  • Mild staphylococcus
Self limiting 
Cleansing and local antiseptic

  • Severe
Topical and systemic antibiotics

  • Recurrent and persistent cases
Prophylaxis against staph in carriage sites


Deep folliculitis

Furuncle
  • A furuncle is an acute, usually necrotic, infection of a hair follicle with S. aureus.


  • Site:

Any site and common site are neck, buttocks and anogenital area.

  • Aetiology

S.aureus
M>F
Most common in adolescence and early adult life.
Tight clothes predisposes
The infecting strain of Staphylococcus is usually also present in the nares or the perineum

Clinical features

  • A furuncle first presents as a small, follicular, inflammatory nodule, soon becoming pustular and then necrotic and healing after discharge of a necrotic core to leave a violaceous macule and, ultimately, a permanent scar.


  • Occasionally, there may be fever and mild constitutional symptoms.





Treatment

  • Antistaphylococcal antibiotics.

Carbuncle
  • A carbuncle is a deep infection of a group of contiguous follicles with S. aureus, accompanied by intense inflammatory changes in the surrounding and underlying connective tissues, including the subcutaneous fat.


  • Aetiology

S.aerues
Common in men (middle or old age)
They may be seen in the apparently healthy but are more common in the presence of diabetes, malnutrition, cardiac failure, drug addiction or severe generalized dermatoses, such as exfoliative dermatitis or pemphigus, and during prolonged steroid therapy.


Clinical features

  • Very tender nodule associated with severe constitutional symptoms.


  • May be upto 10cm in size and discharge in several days.


  • Site: neck, shoulders and hips.





Treatment
  • Antistaphylococcal antibiotics

  • Diabetes and other possible underlying conditions should be sought.

Staphylococcal scalded skin syndrome
  • SSSS is an exfoliative dermatosis in which most of the body surface becomes erythematous and the necrotic superficial epidermis strips off.


  • Occurs predominantly in childern (esp. neonates)


Etiology

  • Staph. Aereus
  • Due to protease like effect of exfoliative toxins
  • Two of the toxins (A and B) cause disruption of the desmosomes by cleaving desmoglein-1 in the most superficial epidermis and also cause the split beneath the stratum corneum which leads to peeling of skin.



Clinical features

  • The initial event is usually a localized staphylococcal infection. This may be in the skin or at a distant or ‘occult’ site.
  • A few days later, patients develop fever, irritability and skin tenderness.
  • A widespread erythematous eruption follows, which progresses rapidly to blister formation.
  • The tender skin becomes gathered into folds and, as it shrinks, leaves raw areas which are extremely painful.
  • The condition usually heals within 7–14 days
  • Swabs and cultures of blister fluids do not usually grow the staphylococci, as the blisters are mediated by the toxins which are disseminated haematogenously. The staphylococci may be isolated from the original septic site.





Treatment


  • Systemic antibiotic:

Flucloxacillin

  • Supportive measures
  • Bacterial swabs from carrier sites- to exclude satph. Carrriage.


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